I have to admit my experience at the Sistine Chapel so many years ago wasn't the most profound. I was there with a friend, in a crowded chapel, the buzz of speeches in various languages all around me. It was tight, uncomfortable, and the Vatican security with their barrel-chest and tight suits kept growling, "No photo!" every time a flash went off.
I found this talk by art historian Elizabeth Lev, and she tells a wonderful tale of the stories in the murals, something that I wished I had a chance to experience when I was there so many years ago. In the setting that I viewed the Sistine Chapel, the story was underwhelming, which was a shame. I did come back from Rome later that year and read Irving Stone's The Agony and the Ecstasy, which tells the story in novel form of Michelangelo's creative life.